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Privacy-first polygenic risk score analysis. Upload your DNA, get trait scores — all processing happens on your device. Built on DuckDB WASM, Web Components, and the PGS Catalog. No accounts, no servers, no data leaves your browser.

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Asili – open-source, privacy-first in-browser DNA PGS scoring

Name: Asili – open-source, privacy-first in-browser DNA PGS scoring
Availability: InStock
Author: techninja42

by techninja42·Jun 18, 2026·3 points·1 comment

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AI Analysis

●●●BangerBig BrainZero to One

DuckDB WASM runs GWAS scoring entirely in-browser when every competitor requires server upload.

Strengths

•DuckDB WASM enables complex variant scoring against PGS Catalog without any server infrastructure.
•Family comparison feature lets you upload multiple members and compare traits side by side.
•IndexedDB persistence means results survive page reloads without accounts or logins.

Weaknesses

•Only 64 traits currently scored; pipeline to expand to 647+ is still in development.
•Ancestry-specific reference populations not yet implemented for normalization.